Jane Naana Opoku-Agyemang’s journey to becoming Ghana’s first female Vice President began with her selection as the running mate for the National Democratic Congress (NDC) in July 2020 for the December 2020 General Elections. This made her the first female running mate from any of the two major political parties in Ghana. Her nomination by John Dramani Mahama was widely applauded by women’s groups and activists, who saw it as a groundbreaking move for gender balance in Ghanaian politics.
Her campaign focused on hope and progress, appealing to Ghanaians to vote for change while pledging to champion youth-centered policies and sustainable development. With her calm demeanor and issue-focused messaging, she avoided engaging in political attacks, earning her widespread respect.
In 2024, the NDC National Executive Committee reaffirmed their confidence in her by endorsing her again as Mahama’s running mate. Their victory in the elections sealed her place in history as Ghana’s first female Vice President. She was sworn into power on the 7th of January, 2025, at the Blackstar Square by the Chief Justice, Gertrude Araba Esaaba Sackey Torkornoo.

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